Longitudinal high-frequency blood biomarkers of axonal injury and astrocytic activation after immune reconstitution in multiple sclerosis

Abstract Background Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) reflect axonal damage and astrocytic injury. Their clinical role in longitudinal real-world monitoring after immune reconstitution therapy (IRT) in multiple sclerosis (MS) remains insufficiently de...

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Bibliografiske detaljer

Principais autores:	Hernan Inojosa, Luise Werder, Rocco Haase, Undine Proschmann, Pascal Benkert, Jens Kuhle, Hagen B Huttner, Tjalf Ziemssen, Katja Akgün
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMC 2025-12-01
Serier:	Journal of Neuroinflammation
Fag:	Neurofilament light chain Glial fibrillary acidic protein Multiple sclerosis Immune reconstitution therapy Disease monitoring
Online adgang:	https://doi.org/10.1186/s12974-025-03674-2
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