Keeping up with the guidelines: design changes to the STREAM stage 2 randomised controlled non-inferiority trial for rifampicin-resistant tuberculosis

Abstract Results from the STREAM stage 1 trial showed that a 9-month regimen for patients with rifampicin-resistant tuberculosis was non-inferior to the 20-month regimen recommended by the 2011 WHO treatment guidelines. Similar levels of severe adverse events were reported on both regimens suggestin...

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Principais autores:	Ruth L. Goodall, Karen Sanders, Gay Bronson, Meera Gurumurthy, Gabriela Torrea, Sarah Meredith, Andrew Nunn, I. D. Rusen, on behalf of the STREAM Trial Team
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2022-06-01
Series:	Trials
Assuntos:	Trial Design Rifampicin resistance tuberculosis
Acceso en liña:	https://doi.org/10.1186/s13063-022-06397-4
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