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QT interval prolongation and cardiotoxicity in shorter regimens for rifampicin-resistant tuberculosis

Objectives: Effective rifampicin-resistant tuberculosis (RR-TB) regimens often include multiple QT-prolonging drugs, necessitating evaluation across different combinations. Methods: Using pooled electrocardiogram data from two trials, three QT-prolonging shorter regimens for RR-TB were studied: the...

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Principais autores: Yilin Zhang, Yang Li, Yuanyuan Chen, Cui Cai, Hengzhong Yi, Qianhong Wu, Yuan Qian, Hongying Yu, Yuanbo Lan, Jichan Shi, Ya Huang, Yungui Zhang, Shun Feng, Mingying Xiao, Jing Wang, Yiming Li, Hua Wang, Zebao He, Haiqing Liu, Yena Zhang, Yong Zhou, Yuqing Wu, Feng Sun, Wenhong Zhang
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2026-06-01
Serier:International Journal of Infectious Diseases
Fag:
Rifampicin-resistant tuberculosis
Shorter oral regimen
QT interval prolongation
Bedaquiline
Clofazimine
Moxifloxacin
Online adgang:http://www.sciencedirect.com/science/article/pii/S1201971226002961
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