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Activation of the mTOR pathway promotes neurite growth through upregulation of CD44 expression

Objective To explore the intrinsic mechanism of the mammalian target of rapamycin (mTOR) pathway activation and promotion of neuronal axon growth. Methods Human neuroblastoma cells, SH-SY5Y, were induced with all-trans retinoic acid (ATRA; 10 μM for three days) which differentiated the cell line int...

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Bibliografische Detailangaben
Hauptverfasser: Jiwei Zhang, Wenjuan Gan, Ru Peng, Lei Lu, Weiqing Lu, Jiamei Liu
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publishing 2023-06-01
Schriftenreihe:Journal of International Medical Research
Online-Zugang:https://doi.org/10.1177/03000605231178510
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