UBTOR/KIAA1024 regulates neurite outgrowth and neoplasia through mTOR signaling.

The mTOR signaling pathways regulate cell growth and are involved in multiple human diseases. Here, we identify UBTOR, a previously unannotated gene as a functional player in regulating cell growth and mTOR signaling. Reduction of UBTOR function in cultured hippocampal neurons and PC12 cells promote...

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Dades bibliogràfiques

Autors principals:	Hefei Zhang, Quan Zhang, Ge Gao, Xinjian Wang, Tiantian Wang, Zhitao Kong, Guoxiang Wang, Cuizhen Zhang, Yun Wang, Gang Peng
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2018-08-01
Col·lecció:	PLoS Genetics
Accés en línia:	http://europepmc.org/articles/PMC6095612?pdf=render
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