Bulk and single-cell transcriptome analysis reveal shared key genes and patterns of immune dysregulation in systemic lupus erythematosus and sepsis

Abstract Systemic lupus erythematosus (SLE) patients often experience sepsis, a significant clinical challenge that frequently requires intensive care and contributes significantly to morbidity and mortality. However, the molecular mechanisms underlying this comorbidity remain poorly understood. Thi...

תיאור מלא

מידע ביבליוגרפי

Principais autores:	Xuehuan Wen, Songjie Bai, Kangwei Sun, Kai Zhang, Ruomeng Hu, Shumin Li, Jie Yang, Lanxin Cao, Zhijian Cai, Gensheng Zhang
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	BMC 2025-12-01
סדרה:	Molecular Medicine
נושאים:	Sepsis Systemic lupus erythematosus PLSCR1 Single-cell transcriptome CD14+ monocyte
גישה מקוונת:	https://doi.org/10.1186/s10020-025-01350-y
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!