Identification of shared neoantigens derived from frameshift mutations in the APC gene

Recent advances of cancer immunotherapy have identified neoantigens as essential targets for personalized treatments. However, since neoantigens are generally unique in individual cancers, neoantigen therapies that are more broadly applicable are eagerly awaited. Shared neoantigens, derived from rec...

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Hlavní autoři:	Peng Zhao, Clara Effenberger, Saki Matsumoto, Toshihiro Tanaka, Yusuke Nakamura, Kazuma Kiyotani
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2025-05-01
Edice:	Frontiers in Immunology
Témata:	cancer immunotherapy frameshift indels frameshift neoantigen shared neoantigens T cell receptor TCR-engineered T cells
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1574955/full
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