The N-Terminal Region of the Transcription Factor E2F1 Contains a Novel Transactivation Domain and Recruits General Transcription Factor GTF2H2
The transcription factor E2F1 is the principal target of the tumor suppressor pRB. E2F1 promotes cell proliferation by activating growth-promoting genes upon growth stimulation. In contrast, E2F1 contributes to tumor suppression by activating tumor suppressor genes, such as <i>ARF</i>, upon loss of...
שמור ב:
| Principais autores: | , , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
MDPI AG
2024-10-01
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| סדרה: | Biomolecules |
| נושאים: | |
| גישה מקוונת: | https://www.mdpi.com/2218-273X/14/11/1357 |
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