Identification of Potential COX-2 Inhibitors for the Treatment of Inflammatory Diseases Using Molecular Modeling Approaches

Non-steroidal anti-inflammatory drugs are inhibitors of cyclooxygenase-2 (COX-2) that were developed in order to avoid the side effects of non-selective inhibitors of COX-1. Thus, the present study aims to identify new selective chemical entities for the COX-2 enzyme via molecular modeling approache...

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主要な著者:	Pedro H. F. Araújo, Ryan S. Ramos, Jorddy N. da Cruz, Sebastião G. Silva, Elenilze F. B. Ferreira, Lúcio R. de Lima, Williams J. C. Macêdo, José M. Espejo-Román, Joaquín M. Campos, Cleydson B. R. Santos
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2020-09-01
シリーズ:	Molecules
主題:	in silico COX-2 inhibitors molecular modeling
オンライン･アクセス:	https://www.mdpi.com/1420-3049/25/18/4183
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