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CircSTX6 promotes pancreatic ductal adenocarcinoma progression by sponging miR-449b-5p and interacting with CUL2

Abstract Background circular RNAs (circRNAs) have been reported to play crucial roles in the biology of different cancers. However, little is known about the function of circSTX6 (hsa_circ_0007905) in pancreatic ductal adenocarcinoma (PDAC). Methods circSTX6, a circRNA containing exons 4, 5, 6 and 7...

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Principais autores: Lingdong Meng, Yihan Zhang, Pengfei Wu, Danrui Li, Yichao Lu, Peng Shen, Taoyue Yang, Guodong Shi, Qun Chen, Hao Yuan, Wanli Ge, Yi Miao, Min Tu, Kuirong Jiang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2022-06-01
Serier:Molecular Cancer
Fag:
Pancreatic ductal adenocarcinoma
circSTX6
miR-449b-5p
HIF1A
MYH9
Online adgang:https://doi.org/10.1186/s12943-022-01599-5
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