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EIF4E-mediated biogenesis of circPHF14 promotes the growth and metastasis of pancreatic ductal adenocarcinoma via Wnt/β-catenin pathway

Abstract Background CircRNAs are critically involved in the development and progression of various cancers. However, their functions and mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain largely unknown. Methods CircPHF14 (hsa_circ_0079440) was identified through the analysis of RNA seque...

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Autori principali: Zhou Fang, Zhuo Wu, Chao Yu, Qingyu Xie, Liangtang Zeng, Rufu Chen
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2025-02-01
Serie:Molecular Cancer
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Accesso online:https://doi.org/10.1186/s12943-025-02262-5
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