EIF4E-mediated biogenesis of circPHF14 promotes the growth and metastasis of pancreatic ductal adenocarcinoma via Wnt/β-catenin pathway

Abstract Background CircRNAs are critically involved in the development and progression of various cancers. However, their functions and mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain largely unknown. Methods CircPHF14 (hsa_circ_0079440) was identified through the analysis of RNA seque...

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Bibliografische Detailangaben

Hauptverfasser:	Zhou Fang, Zhuo Wu, Chao Yu, Qingyu Xie, Liangtang Zeng, Rufu Chen
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2025-02-01
Schriftenreihe:	Molecular Cancer
Schlagworte:	Pancreatic ductal adenocarcinoma circPHF14 WNT7A PABPC1 EIF4E LNP
Online-Zugang:	https://doi.org/10.1186/s12943-025-02262-5
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