Combined subtractive cDNA cloning and array CGH: an efficient approach for identification of overexpressed genes in DNA amplicons

<p>Abstract</p> <p>Background</p> <p>Activation of proto-oncogenes by DNA amplification is an important mechanism in the development and maintenance of cancer cells. Until recently, identification of the targeted genes relied on labour intensive and time consuming positional cloning methods. In this...

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Principais autores:	De Paepe Anne, Van Roy Frans, Menten Björn, Strumane Kristin, Pattyn Filip, Berx Geert, De Preter Katleen, Speleman Frank, Vandesompele Jo
格式:	Artigo
语言:	Inglês
出版:	BMC 2004-02-01
丛编:	BMC Genomics
主题:	Amplification Overexpression Oncogene SSH Array CGH Neuroblastoma
在线阅读:	http://www.biomedcentral.com/1471-2164/5/11
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