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Non-replicating adenovirus based Mayaro virus vaccine elicits protective immune responses and cross protects against other alphaviruses.

Mayaro virus (MAYV) is an alphavirus endemic to South and Central America associated with sporadic outbreaks in humans. MAYV infection causes severe joint and muscle pain that can persist for weeks to months. Currently, there are no approved vaccines or therapeutics to prevent MAYV infection or trea...

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Bibliografiske detaljer
Principais autores: John M Powers, Nicole N Haese, Michael Denton, Takeshi Ando, Craig Kreklywich, Kiley Bonin, Cassilyn E Streblow, Nicholas Kreklywich, Patricia Smith, Rebecca Broeckel, Victor DeFilippis, Thomas E Morrison, Mark T Heise, Daniel N Streblow
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2021-04-01
Serier:PLoS Neglected Tropical Diseases
Online adgang:https://doi.org/10.1371/journal.pntd.0009308
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