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Generation and characterization of infectious clones of chikungunya virus from an Indian strain as a resource towards chikungunya vaccine research

India has witnessed several devastating chikungunya virus (CHIKV) epidemics since 2005. Developing a stable reverse genetic system using Indian CHIKV strains will be paramount to studying the molecular mechanism of CHIKV pathogenesis.We generated the first infectious clone (IC) of an Indian isolate...

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Principais autores: Garvita Mathur, Shakuntala Mahilkar, Sujatha Sunil
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2025-06-01
coleção:Virus Research
Assuntos:
Chikungunya virus (CHIKV)
Infectious clone (IC)
Genetic determinants
Virus pathogenesis
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0168170225000486
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