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Nef-specific CD45RA+ CD8+ T cells secreting MIP-1β but not IFN-γ are associated with nonprogressive HIV-1 infection

<p>Abstract</p> <p>Background</p> <p>Long-term survival of HIV-1 infected individuals is usually achieved by continuous administration of combination antiretroviral therapy (ART). An exception to this scenario is represented by HIV-1 infected nonprogressors (NP) which maintain relatively high circul...

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Principais autores: Goebel Frank D, Vollbrecht Thomas, Santagostino Elena, Stellbrink Hans-J, Lusso Paolo, Bogner Johannes R, Tambussi Giuseppe, Reitmeir Peter, Hoffmann Dieter, Vicenzi Elisa, Ghezzi Silvia, Biswas Priscilla, Allgayer Simone, Heltai Silvia, Kutscher Sarah, Dembek Claudia J, Protzer Ulrike, Draenert Rika, Tinelli Marco, Poli Guido, Erfle Volker, Malnati Mauro, Cosma Antonio
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2010-07-01
Serier:AIDS Research and Therapy
Online adgang:http://www.aidsrestherapy.com/content/7/1/20
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