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The intracellular detection of MIP-1beta enhances the capacity to detect IFN-gamma mediated HIV-1-specific CD8 T-cell responses in a flow cytometric setting providing a sensitive alternative to the ELISPOT

<p>Abstract</p> <p>Background</p> <p>T-cell mediated immunity likely plays an important role in controlling HIV-1 infection and progression to AIDS. Several candidate vaccines against HIV-1 aim at stimulating cellular immune responses, either alone or together with the induction of neutralizing anti...

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Principais autores: Goebel Frank D, Stellbrink Hans J, Bogner Johannes R, Tambussi Giuseppe, Nozza Silvia, Biswas Priscilla, Stadlbauer Birgit, Heltai Silvia, Allgayer Simone, Dembek Claudia J, Kutscher Sarah, Lusso Paolo, Tinelli Marco, Poli Guido, Erfle Volker, Pohla Heike, Malnati Mauro, Cosma Antonio
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2008-10-01
Serier:AIDS Research and Therapy
Online adgang:http://www.aidsrestherapy.com/content/5/1/22
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