Regulatory effects of arachidonate 5-lipoxygenase on hepatic microsomal TG transfer protein activity and VLDL-triglyceride and apoB secretion in obese mice

As 5-lipoxygenase (5-LO) is an emerging target in obesity and insulin resistance, we have investigated whether this arachidonate pathway is also implicated in the progression of obesity-related fatty liver disease. Our results show that 5-LO activity and 5-LO-derived product levels are significantly...

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Bibliografische Detailangaben

Hauptverfasser:	Marta López-Parra, Esther Titos, Raquel Horrillo, Natàlia Ferré, Ana González-Périz, Marcos Martínez-Clemente, Anna Planagumà, Jaime Masferrer, Vicente Arroyo, Joan Clària
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2008-12-01
Schriftenreihe:	Journal of Lipid Research
Schlagworte:	arachidonate 5-LO VLDL-TG hepatic steatosis
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S0022227520345831
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