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Current and future concepts for the generation and application of genetically engineered CAR-T and TCR-T cells

Adoptive cell therapy (ACT) has seen a steep rise of new therapeutic approaches in its immune-oncology pipeline over the last years. This is in great part due to the recent approvals of chimeric antigen receptor (CAR)-T cell therapies and their remarkable efficacy in certain soluble tumors. A big fo...

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Principais autores: Michael Hiltensperger, Angela M. Krackhardt
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-03-01
Colecção:Frontiers in Immunology
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1121030/full
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