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Engineering TCR-directed T-cells for the treatment of multiple myeloma

Multiple myeloma (MM) is a virtually incurable plasma cell malignancy characterized by malignant cells that expand within the tumor-permissive bone marrow (BM) microenvironment. Novel strategies are urgently needed to improve the outcomes of patients with difficult-to-treat and therapy-refractory di...

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Bibliografiske detaljer
Principais autores: Nida Mubin, James J. Ignatz-Hoover, James J. Driscoll
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-03-01
Serier:Frontiers in Immunology
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1755096/full
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