MAFB regulates hematopoietic stem cell proliferation and maintenance

Abstract MAFB, a transcription factor of the large Maf family, is expressed in both fetal liver (FL) and bone marrow (BM) hematopoietic stem cells (HSCs). However, its stage-specific roles remain elusive. Here, we reveal that MAFB plays distinct roles in FL and BM HSCs. Using Mafb-deficient and Mafb...

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מידע ביבליוגרפי

Principais autores:	Saki Asano, Ching-Wei Liao, Yurina Matsunaga, Hyojung Jeon, Kyoko Sawaguchi, Keigo Asano, Manabu Kusakabe, Zeynab Javanfekr Shahri, Natalia Gogoleva, Tomomasa Yokomizo, Satoru Takahashi, Michito Hamada
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Nature Portfolio 2025-11-01
סדרה:	Scientific Reports
נושאים:	MAFB Hematopoietic stem cells (HSCs) Self-renewal Cell cycle regulation Stem cell exhaustion
גישה מקוונת:	https://doi.org/10.1038/s41598-025-24389-7
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