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Long-chain acyl-CoA synthetases: biological functions, diseases and therapeutic targets

Abstract The long-chain acyl-CoA synthetase (ACSL) family comprises key enzymes that are integral to the fatty acid metabolic pathway and play crucial roles in governing fatty acid (FA) metabolism and lipid homeostasis. These enzymes are involved in multiple pathophysiological processes, including c...

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Hlavní autoři: Xiaoliang Deng, Yanqun Luo, Ying Gao, Tao Wu
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer 2025-11-01
Edice:Molecular Biomedicine
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On-line přístup:https://doi.org/10.1186/s43556-025-00366-4
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