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scHolography: a computational method for single-cell spatial neighborhood reconstruction and analysis

Abstract Spatial transcriptomics has transformed our ability to study tissue complexity. However, it remains challenging to accurately dissect tissue organization at single-cell resolution. Here we introduce scHolography, a machine learning-based method designed to reconstruct single-cell spatial ne...

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Hlavní autoři: Yuheng C. Fu, Arpan Das, Dongmei Wang, Rosemary Braun, Rui Yi
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2024-06-01
Edice:Genome Biology
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On-line přístup:https://doi.org/10.1186/s13059-024-03299-3
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