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Bioinformatic Analysis of Deleterious Non-Synonymous Single Nucleotide Polymorphisms (nsSNPs) in the Coding Regions of Human Prion Protein Gene (PRNP)

Background & Objective: Single nucleotide polymorphisms are the cause of genetic variation to living organisms. Single nucleotide polymorphisms alter residues in the protein sequence. In this investigation, the relationship between prion protein gene polymorphisms and its relevance to pathogenicity...

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Autors principals: Kourosh Bamdad, Fatemeh Rahimi Gharemirshamlu, Sirous Naeimi
Format: Artigo
Idioma:Inglês
Publicat: Fasa University of Medical Sciences 2016-11-01
Col·lecció:Journal of Advanced Biomedical Sciences
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Accés en línia:http://jabs.fums.ac.ir/article-1-1088-en.pdf
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