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Mitochondria and Lipid Defects in Hereditary Progranulin-Related Frontotemporal Dementia

Frontotemporal dementia (FTD) is a neurodegenerative disorder predominantly affecting individuals under 65 years of age, characterized by significant behavioral and language disabilities. Despite extensive research efforts, effective treatments for FTD remain elusive. Familial cases of FTD have been...

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Autori principali: Jon Ondaro, Jose Luis Zúñiga-Elizari, Mónica Zufiría, Maddi Garciandia-Arcelus, Ángela Sánchez Molleda, Miren Zulaica, Miguel Lafarga, Javier Riancho, Adolfo López de Munaín, Fermin Moreno, Francisco Javier Gil-Bea, Gorka Gerenu
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2026-02-01
Serie:Cells
Soggetti:
lysosome
mitochondria
progranulin
GRN
frontotemporal dementia
FTD
Accesso online:https://www.mdpi.com/2073-4409/15/3/276
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