Small animal PET imaging with the 68Ga-labeled pH (low) insertion peptide-like peptide YJL-4 in a triple-negative breast cancer mouse model

Abstract Background The aim of this study was to prepare a novel 68Ga-labeled pH (low) insertion peptide (pHLIP)-like peptide, YJL-4, and determine its value for the early diagnosis of triple-negative breast cancer (TNBC) via in vivo imaging of tumor-bearing nude mice. The novel peptide YJL-4 was de...

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Autors principals:	YueHua Chen, ShuangShuang Song, YanQin Sun, FengYu Wu, GuangJie Yang, ZhenGuang Wang, MingMing Yu
Format:	Artigo
Idioma:	Inglês
Publicat:	SpringerOpen 2024-04-01
Col·lecció:	EJNMMI Radiopharmacy and Chemistry
Matèries:	Triple-negative breast cancer Tumor microenvironment pH (low) insertion peptides 68Ga Small animal PET/CT Molecular imaging
Accés en línia:	https://doi.org/10.1186/s41181-024-00267-x
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