Pharmacological Inhibition of the PI3K/AKT/mTOR Pathway in Rheumatoid Arthritis Synoviocytes: A Systematic Review and Meta-Analysis (Preclinical)

<b>Background/Objectives</b>: Constitutive activation of the PI3K/AKT/mTOR signaling cascade underlies the aggressive phenotype of fibroblast-like synoviocytes (FLSs) in rheumatoid arthritis (RA); however, a quantitative synthesis of in vitro data on pathway inhibition remains lacking. This systemat...

Volledige beschrijving

Bibliografische gegevens

Hoofdauteurs:	Tatiana Bobkova, Artem Bobkov, Yang Li
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	MDPI AG 2025-08-01
Reeks:	Pharmaceuticals
Onderwerpen:	rheumatoid arthritis fibroblast-like synoviocytes PI3K/AKT/mTOR pathway inhibition p-AKT p-mTOR
Online toegang:	https://www.mdpi.com/1424-8247/18/8/1152
Tags:	Voeg label toe Geen labels, Wees de eerste die dit record labelt!