Preliminary SAR of Novel Pleuromutilin–Polyamine Conjugates
While pleuromutilin (<b>1</b>) and its clinically available derivatives (<b>2</b>–<b>6</b>) are highly effective against Gram-positive bacteria, they remain inactive against many pathogenic Gram-negative bacteria due to the efflux pump AcrAB-TolC. In an effort to broaden the spectrum of activity of...
Gorde:
| Egile Nagusiak: | , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
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MDPI AG
2023-11-01
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| Saila: | Microorganisms |
| Gaiak: | |
| Sarrera elektronikoa: | https://www.mdpi.com/2076-2607/11/11/2791 |
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