Prions amplify through degradation of the VPS10P sorting receptor sortilin.
Prion diseases are a group of fatal neurodegenerative disorders caused by prions, which consist mainly of the abnormally folded isoform of prion protein, PrPSc. A pivotal pathogenic event in prion disease is progressive accumulation of prions, or PrPSc, in brains through constitutive conformational...
Spremljeno u:
| Glavni autori: | , , , , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science (PLoS)
2017-06-01
|
| Serija: | PLoS Pathogens |
| Online pristup: | https://doi.org/10.1371/journal.ppat.1006470 |
| Oznake: |
Bez oznaka, Budi prvi tko označuje ovaj zapis!
|