Novel switchable ECF sigma factor transcription system for improving thaxtomin A production in Streptomyces

The application of the valuable natural product thaxtomin A, a potent bioherbicide from the potato scab pathogenic Streptomyces strains, has been greatly hindered by the low yields from its native producers. Here, we developed an orthogonal transcription system, leveraging extra-cytoplasmic function...

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Hlavní autoři:	Xuejin Zhao, Weijia Wei, Yeqing Zong, Chaoxian Bai, Xian Guo, Hua Zhu, Chunbo Lou
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	KeAi Communications Co., Ltd. 2022-09-01
Edice:	Synthetic and Systems Biotechnology
Témata:	Streptomyces ECF17 sigma factor Heterologous expression Thaxtomin A Transcription system
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2405805X22000576
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