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Novel switchable ECF sigma factor transcription system for improving thaxtomin A production in Streptomyces

The application of the valuable natural product thaxtomin A, a potent bioherbicide from the potato scab pathogenic Streptomyces strains, has been greatly hindered by the low yields from its native producers. Here, we developed an orthogonal transcription system, leveraging extra-cytoplasmic function...

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Bibliografiske detaljer
Principais autores: Xuejin Zhao, Weijia Wei, Yeqing Zong, Chaoxian Bai, Xian Guo, Hua Zhu, Chunbo Lou
Format: Artigo
Sprog:Inglês
Udgivet: KeAi Communications Co., Ltd. 2022-09-01
Serier:Synthetic and Systems Biotechnology
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Online adgang:http://www.sciencedirect.com/science/article/pii/S2405805X22000576
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