Physicochemical Effects of the Major Quassinoids in a Standardized Extract (Fr 2) on the Bioavailability and Pharmacokinetic Properties, and their Implications for Oral Antimalarial Activity
A simple validated LC-UV method for the phytochemical analysis of four bioactive quassinoids, 13α(21)-epoxyeurycomanone ( EP ), eurycomanone ( EN ), 13α,21-dihydroeurycomanone ( ED ) and eurycomanol ( EL ) in rat plasma following oral (200 mg/kg) and intravenous administration (10 mg/kg) of a standa...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publishing
2011-03-01
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| coleção: | Natural Product Communications |
| Acesso em linha: | https://doi.org/10.1177/1934578X1100600307 |
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