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Physicochemical Effects of the Major Quassinoids in a Standardized Extract (Fr 2) on the Bioavailability and Pharmacokinetic Properties, and their Implications for Oral Antimalarial Activity

A simple validated LC-UV method for the phytochemical analysis of four bioactive quassinoids, 13α(21)-epoxyeurycomanone ( EP ), eurycomanone ( EN ), 13α,21-dihydroeurycomanone ( ED ) and eurycomanol ( EL ) in rat plasma following oral (200 mg/kg) and intravenous administration (10 mg/kg) of a standa...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Bin-Seng Low, Chin-Hoe Teh, Kah-Hay Yuen, Kit-Lam Chan
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publishing 2011-03-01
Schriftenreihe:Natural Product Communications
Online-Zugang:https://doi.org/10.1177/1934578X1100600307
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