Triptolide attenuates cardiac remodeling by inhibiting pyroptosis and EndMT via modulating USP14/Keap1/Nrf2 pathway

Background: Cardiac remodeling is a common pathological feature in many cardiac diseases, characterized by cardiac hypertrophy and fibrosis. Triptolide (TP) is a natural compound derived from Tripterygium wilfordii Hook F. However, the related mechanism of it in cardiac remodeling has not been fully...

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主要な著者:	Lina Ba, Mingyao E, Ruixuan Wang, Nan Wu, Rui Wang, Renling Liu, Xiang Feng, Hanping Qi, Hongli Sun, Guofen Qiao
フォーマット:	Artigo
言語:	Inglês
出版事項:	Elsevier 2024-01-01
シリーズ:	Heliyon
主題:	Triptolide Cardiac remodeling Cardiac hypertrophy Cardiac fibrosis Pyroptosis EndMT
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2405844024000410
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