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Genetic interference with HvNotch provides new insights into the role of the Notch-signalling pathway for developmental pattern formation in Hydra

Abstract The Notch-signalling pathway plays an important role in pattern formation in Hydra. Using pharmacological Notch inhibitors (DAPT and SAHM1), it has been demonstrated that HvNotch is required for head regeneration and tentacle patterning in Hydra. HvNotch is also involved in establishing the...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Qin Pan, Moritz Mercker, Alexander Klimovich, Jörg Wittlieb, Anna Marciniak-Czochra, Angelika Böttger
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Portfolio 2024-04-01
Saila:Scientific Reports
Sarrera elektronikoa:https://doi.org/10.1038/s41598-024-58837-7
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