Lipid metabolism dysregulation in rheumatoid arthritis: from multi-omics discovery to adjunctive therapy with conjugated linoleic acid

Abstract Objective This study aims to comprehensively analyze the role of metabolic signatures in rheumatoid arthritis (RA). Methods A total of 599 samples, including fecal (n = 206), plasma (n = 206), and peripheral blood mononuclear cell (PBMC) samples (n = 187), were collected from 443 individual...

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Auteurs principaux:	Jianghua Chen, Zhuming Yin, Wantai Dang, Congcong Jian, Tingting Wang, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Jing Gao, Jie Zhang, Jiang Su, Jing Zhu, Jianhong Wu, Qinghua Zou, Pilei Si, Fanxin Zeng
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2026-05-01
Collection:	Arthritis Research & Therapy
Sujets:	Rheumatoid arthritis Metabolic signatures Multiomics analysis Linoleic acid metabolism Conjugated linoleic acid
Accès en ligne:	https://doi.org/10.1186/s13075-026-03831-9
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