Lipid metabolism dysregulation in rheumatoid arthritis: from multi-omics discovery to adjunctive therapy with conjugated linoleic acid

Abstract Objective This study aims to comprehensively analyze the role of metabolic signatures in rheumatoid arthritis (RA). Methods A total of 599 samples, including fecal (n = 206), plasma (n = 206), and peripheral blood mononuclear cell (PBMC) samples (n = 187), were collected from 443 individual...

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Autores principales:	Jianghua Chen, Zhuming Yin, Wantai Dang, Congcong Jian, Tingting Wang, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Jing Gao, Jie Zhang, Jiang Su, Jing Zhu, Jianhong Wu, Qinghua Zou, Pilei Si, Fanxin Zeng
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2026-05-01
Colección:	Arthritis Research & Therapy
Materias:	Rheumatoid arthritis Metabolic signatures Multiomics analysis Linoleic acid metabolism Conjugated linoleic acid
Acceso en línea:	https://doi.org/10.1186/s13075-026-03831-9
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