Contribution of neuroblastoma-derived exosomes to the production of pro-tumorigenic signals by bone marrow mesenchymal stromal cells

The bone marrow (BM) niche is a microenvironment promoting survival, dormancy and therapeutic resistance in tumor cells. Central to this function are mesenchymal stromal cells (MSCs). Here, using neuroblastoma (NB) as a model, we demonstrate that NB cells release an extracellular vesicle (EVs) whose...

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Principais autores:	Rie Nakata, Hiroyuki Shimada, G. Esteban Fernandez, Rob Fanter, Muller Fabbri, Jemily Malvar, Pascale Zimmermann, Yves A. DeClerck
格式:	Artigo
語言:	Inglês
出版:	Wiley 2017-12-01
叢編:	Journal of Extracellular Vesicles
主題:	Exosomes mesenchymal stromal cells cell–cell interaction extracellular vesicles extracellular-signal-regulated kinase neuroblastoma
在線閱讀:	http://dx.doi.org/10.1080/20013078.2017.1332941
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