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Synthesis and Preliminary Evaluation of FAPα Targeted Tracer 131I-FAPI-03

Abstract: Using N-(4-quinolinoyl)-Gly-(2-cyanopyrrolidine) as scaffold, we prolonged the linker with serine to obtain a FAPI derivative ATE-FAPI-03, which was subsequently labeled with 131I by electrophilic substitution. Then the in vitro stability, Log P value, binding affinity, targeting propertie...

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Bibliografische gegevens
Hoofdauteur: MA Huan1, 2, LIAO Jiali2, YANG Yuanyou2, LIU Ning2, LI Feize2
Formaat: Artigo
Taal:Chinês
Gepubliceerd in: Editorial Board of Journal of Isotopes 2024-04-01
Reeks:Journal of Isotopes
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Online toegang:https://tws.xml-journal.net/cn/article/doi/10.7538/tws.2024.37.02.0097
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