Synthesis and Preliminary Evaluation of FAPα Targeted Tracer 131I-FAPI-03
Abstract: Using N-(4-quinolinoyl)-Gly-(2-cyanopyrrolidine) as scaffold, we prolonged the linker with serine to obtain a FAPI derivative ATE-FAPI-03, which was subsequently labeled with 131I by electrophilic substitution. Then the in vitro stability, Log P value, binding affinity, targeting propertie...
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| Formato: | Artigo |
| Idioma: | Chinês |
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Editorial Board of Journal of Isotopes
2024-04-01
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| Series: | Journal of Isotopes |
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| Acceso en liña: | https://tws.xml-journal.net/cn/article/doi/10.7538/tws.2024.37.02.0097 |
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