A poly-neoantigen DNA vaccine synergizes with PD-1 blockade to induce T cell-mediated tumor control

The combination of immune-stimulating strategies has the potency to improve immunotherapy of cancer. Vaccination against neoepitopes derived from patient tumor material can generate tumor-specific T cell immunity, which could reinforce the efficacy of checkpoint inhibitor therapies such as anti-PD-1...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Elena Tondini, Tsolere Arakelian, Koen Oosterhuis, Marcel Camps, Suzanne van Duikeren, Wanda Han, Ramon Arens, Gerben Zondag, Jeroen van Bergen, Ferry Ossendorp
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis Group 2019-11-01
Edice:	OncoImmunology
Témata:	dna vaccination neoantigens anti-pd-1 cancer immunotherapy
On-line přístup:	http://dx.doi.org/10.1080/2162402X.2019.1652539
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!