Phosphorylation of NFATC1 at PIM1 target sites is essential for its ability to promote prostate cancer cell migration and invasion

Abstract Background Progression of prostate cancer from benign local tumors to metastatic carcinomas is a multistep process. Here we have investigated the signaling pathways that support migration and invasion of prostate cancer cells, focusing on the role of the NFATC1 transcription factor and its...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Sini K. Eerola, Niina M. Santio, Sanni Rinne, Petri Kouvonen, Garry L. Corthals, Mauro Scaravilli, Giovanni Scala, Angela Serra, Dario Greco, Pekka Ruusuvuori, Leena Latonen, Eeva-Marja Rainio, Tapio Visakorpi, Päivi J. Koskinen
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2019-11-01
Σειρά:	Cell Communication and Signaling
Θέματα:	Prostate cancer Metastatic carcinoma NFATC1 PIM kinases Cell motility
Διαθέσιμο Online:	http://link.springer.com/article/10.1186/s12964-019-0463-y
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