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Motif models proposing independent and interdependent impacts of nucleotides are related to high and low affinity transcription factor binding sites in Arabidopsis

Position weight matrix (PWM) is the traditional motif model representing the transcription factor (TF) binding sites. It proposes that the positions contribute independently to TFs binding affinity, although this hypothesis does not fit the data perfectly. This explains why PWM hits are missing in a...

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Autors principals: Anton V. Tsukanov, Victoria V. Mironova, Victor G. Levitsky
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2022-07-01
Col·lecció:Frontiers in Plant Science
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fpls.2022.938545/full
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