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Melatonin ameliorates myocardial injury by reducing apoptosis and autophagy of cardiomyocytes in a rat cardiopulmonary bypass model

Background Myocardial injury is a frequent complication after cardiac surgery with cardiopulmonary bypass (CPB). This study aimed to test the hypothesis that melatonin could attenuate myocardial injury in a rat CPB model. Methods Eighteen male Sprague-Dawley rats were randomly divided into three gro...

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Principais autores: Xiaolin Huang, Jian Hou, Suiqing Huang, Kangni Feng, Yuan Yue, Huayang Li, Shaojie Huang, Mengya Liang, Guangxian Chen, Zhongkai Wu
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2021-04-01
coleção:PeerJ
Assuntos:
Cardiopulmonary bypass
Melatonin
Myocardial protection
Apoptosis
Autophagy
Acesso em linha:https://peerj.com/articles/11264.pdf
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