Melatonin ameliorates myocardial injury by reducing apoptosis and autophagy of cardiomyocytes in a rat cardiopulmonary bypass model

Background Myocardial injury is a frequent complication after cardiac surgery with cardiopulmonary bypass (CPB). This study aimed to test the hypothesis that melatonin could attenuate myocardial injury in a rat CPB model. Methods Eighteen male Sprague-Dawley rats were randomly divided into three gro...

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Autori principali:	Xiaolin Huang, Jian Hou, Suiqing Huang, Kangni Feng, Yuan Yue, Huayang Li, Shaojie Huang, Mengya Liang, Guangxian Chen, Zhongkai Wu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	PeerJ Inc. 2021-04-01
Serie:	PeerJ
Soggetti:	Cardiopulmonary bypass Melatonin Myocardial protection Apoptosis Autophagy
Accesso online:	https://peerj.com/articles/11264.pdf
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