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Human natural killer cell maturation defect supports in vivo CD56(bright) to CD56(dim) lineage development.

Two populations of human natural killer (NK) cells can be identified in peripheral blood. The majority are CD3(-)CD56(dim) cells while the minority exhibits a CD3(-)CD56(bright) phenotype. In vitro evidence indicates that CD56(bright) cells are precursors of CD56(dim) cells, but in vivo evidence is...

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Principais autores: Carolina Inés Domaica, Mercedes Beatriz Fuertes, Ignacio Uriarte, María Victoria Girart, Jessica Sardañons, Dorina Ileana Comas, Daniela Di Giovanni, María Isabel Gaillard, Liliana Bezrodnik, Norberto Walter Zwirner
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2012-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC3519873?pdf=render
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