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Discontinuous template switching generates coronavirus subgenomic RNAs from the 3ʹ viral genome end by 5ʹ to 3ʹ transcription

ABSTRACT In coronavirus (CoV)-infected cells, several structural and accessory proteins are synthesized from subgenome RNAs (sgRNA) containing a common genomic 5ʹ-leader followed by a given open reading frame (ORF). We report that the abundance of these sgRNAs varies with distance from the 3′-end of...

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Váldodahkkit: Ayslan Castro Brant, Zhe Hu, Angelika Zelma Chen, Vladimir Majerciak, Jonathan Yewdell, Zhi-Ming Zheng
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: American Society for Microbiology 2025-10-01
Ráidu:Journal of Virology
Fáttát:
Liŋkkat:https://journals.asm.org/doi/10.1128/jvi.01438-25
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