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Assessment of Substrate Status of Drugs Metabolized by Polymorphic Cytochrome P450 (CYP) 2 Enzymes: An Analysis of a Large-Scale Dataset

Background: The analysis of substrates of polymorphic cytochrome P450 (CYP) enzymes is important information to enable drug–drug interactions (DDIs) analysis and the relevance of pharmacogenetics in this context in large datasets. Our aim was to compare different approaches to assess the substrate p...

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Príomhchruthaitheoirí: Jakob Sommer, Justyna Wozniak, Judith Schmitt, Jana Koch, Julia C. Stingl, Katja S. Just
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: MDPI AG 2024-01-01
Sraith:Biomedicines
Ábhair:
Rochtain ar líne:https://www.mdpi.com/2227-9059/12/1/161
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