Assessment of Substrate Status of Drugs Metabolized by Polymorphic Cytochrome P450 (CYP) 2 Enzymes: An Analysis of a Large-Scale Dataset

Background: The analysis of substrates of polymorphic cytochrome P450 (CYP) enzymes is important information to enable drug–drug interactions (DDIs) analysis and the relevance of pharmacogenetics in this context in large datasets. Our aim was to compare different approaches to assess the substrate p...

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Главные авторы:	Jakob Sommer, Justyna Wozniak, Judith Schmitt, Jana Koch, Julia C. Stingl, Katja S. Just
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2024-01-01
Серии:	Biomedicines
Предметы:	cytochrome P450 enzyme CYP2 drug–drug–gene interaction drug–drug interaction pharmacogenetics pharmacogenomics
Online-ссылка:	https://www.mdpi.com/2227-9059/12/1/161
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