Microgranular acute promyelocytic leukemia with concurrent FLT3-TKD mutation and MYC amplification: expanding the genomic spectrum and guiding personalized therapy
Abstract Background Acute promyelocytic leukemia (APL) is highly curable with targeted therapy combining all-trans retinoic acid (ATRA) and arsenic trioxide, yet the microgranular variant (M3v) frequently mimics monocytic leukemia and may delay diagnosis. Although FLT3 internal tandem duplications a...
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| Formato: | Artigo |
| Idioma: | Inglês |
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Springer
2026-07-01
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| Series: | Journal of Rare Diseases |
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| Acceso en liña: | https://doi.org/10.1007/s44162-026-00217-y |
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